Unravelling the molecular and cellular mechanism of metastasis

Magdalena Szurkowska
Faculty of Medicine

Metastasis is the primary cause of cancer deaths. Understanding mechanisms by which the metastatic initiating cells successfully establish a secondary tumour at a distant site from their primary tumour is important to improve diagnosis, prevention and treatment of metastasis.

Magdalena Szurkowska will join Cedric Blanpain’s team (Stem cell and Cancer Lab’). She will use a technique that enables tracing of over 200’000 tumour genetic clones in in two different mouse models of cell and breast cancers. Their transcriptional profiles will allow to define the cellular and molecular mechanisms that regulate the metastatic cascade in vivo. MS project will also study the role of various fibroblast sub-populations in affecting the extravasion and establishment of tumour cells at the site of metastasis.

End of project: 29-01-2022

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 847012
Created on February 12, 2020