Technology offers

The University is implementing a strategy aiming to protect and manage its intellectual property and transfer its research results to society. ULB-KTO takes care of filing patents and trademarks, as well as protecting know-how and software.

ULB-KTO currently manages a portfolio of 130 active technologies, 91 of which are protected by a family of patents.
Companies that are interested in this may negotiate licensing contracts or collaboration agreements with the University, in order to develop available technologies and/or release them on the market.

See the technologies currently available:

Life Sciences & Health

• CD321-based methodologies for enhanced detection, quantification and isolation of tumor cells and circulating tumor cells

  The technology uses CD321 as a universal marker for more accurate detection and isolation of tumor cells and CTCs, overcoming limitations of traditional markers affected by EMT.

• Cell lines with increased radiotolerance through heterologous expression of a Bdelloid Rotifer DNA ligase

  Radiation tolerance , Engineered cell lines, Space research, Cancer research.

• Cellulose Derived Biopesticide Activating the Plant Immune System

  Phytopharmaceutical compositions based on cellobionic acid to trigger plant defense responses, thus enhancing plant resistance to pathogens.

• Device for cold plasma treatment

  New device and treatment using cold atmospheric plasma for ablation of the duodenal lining or regeneration of the mucosa.

• DPP6 – FXYD2 biomarkers for imaging and targeting Beta-Cells

  New biomarkers expressed in pancreatic beta cells for imaging and targeting beta cells.

• Generation of lung and thyroid organoids from human embryonic stem cells

  New process for creating thyroid and lung tissues from stem cells, achieving all cell types from both organs with high efficiency, while cells autonomously organize into organoids.

• Minimally invasive anchoring system

  Mini-invasive anchoring, Suturing, Stapling, Electrical stimulation, Percutaneous implantation, Single incision laparoscopy, Soft tissue.

• Nanobodies to potentiate cystic fibrosis treatments

  This technology aims to potentiate approved treatment for cystic fibrosis by enhancing the thermal stability of the faulty cystic fibrosis transmembrane conductance regulator (CFTR) protein. In vitro, these patented nanobodies improved the efficacy of the currently approved gold standard treatment (combination of Elexacaftor, Tezacaftor and Ivacaftor) on chloride ion transport.

• Neurological health assessment by peripheral measurement of brain sensorimotor oscillations

  Method to record β-sensorimotor cortical oscillations based on wearable mechanical vibration sensors for assessment and monitoring of neurological health enabling to bypass the use of more expensive and complex EEG or MEG modalities.

• New group A Streptococcus vaccine antigen

  The present invention is at least in part based on the inventors’ discovery that peptides derived from group A Streptococcus (GAS) Enn protein can induce a meaningful immune-protective response against GAS bacteria in test subjects. 

• Optical force transducer

  Medical device - Force Sensing - Force Feedback - Minimally invasive.

• Prognostic biomarker of COVID-19 severity and risks of sequelae post-acute infection

  Biomarker, In Vitro Diagnosis/Prognosis, COVID-19, Disease Severity

• Protein Tyrosine Phosphatase Receptor Kappa (PTPRK) Inhibitors for Treating Obesity-Induced Pathologies

  Small molecule inhibitors of Protein Tyrosine Phosphatase Receptor Kappa (PTPRK) for use in the treatment of obesity and obesity-induced pathologies including metabolic dysfunction-associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC).

• Protein Tyrosine Phosphatases-mediated prognosis of obesity-induced hepatocellular carcinoma

  Novel diagnostic and prognostic assay relying on the expression and oxidation levels of Protein Tyrosine Phosphatases (PTPs) of Hepatocellular carcinoma (HCC).

Materials & Engineering

• Atmospheric plasma deposition of Crystalline inorganic coatings

  The invention of an induction heating system adapted to a reactor of the 'dielectricbarrier discharge' type known as DBD, opened up the field of crystalline deposits of inorganic material hitherto limited to deposition under vacuum or at very high temperature.

• Coriolopsis gallica thermostable laccase

  New method of thermoresistant laccases production using white-rot fungus Coriolopsis gallica.

• Device and method for detecting ice formation

  New devices and methods for detecting the occurrence of icing conditions or ice formation and accretion.

• Device for cold plasma treatment

  New device and treatment using cold atmospheric plasma for ablation of the duodenal lining or regeneration of the mucosa.

• Embedded piezoelectric transducers for ultrasonic monitoring of concrete structures

  The development of low-cost ultrasonic piezoelectric transducers to be embedded in concrete with applications in the field of non-destructive testing techniques (estimation of material properties from the very early age) and structural health monitoring (damage detection, on-line monitoring of civil infrastructure).

• Environmentally-friendly process for recovering gold from Waste from Electrical and Electronic Equipment (WEEE or e-waste)

  A gold leaching solution using environmentally-friendly chemistry, easy to implement and allowing an easy recovery of dissolved gold downstream of the process.

• Holographic sensor for potentially explosive atmospheres (ATEX) monitoring

  Our invention performs in time a 3D imaging process within a volume to allow to count particles, even fastly moving, and to measure their sizes to determine the corresponding statistics on the cloud and concentrations.

• Hygroscopic composite material & salt apparatus

  Nomastock/Corrostock are two patents developing an innovative thermal energy storage method, using a new composite material (Nomastock) and a new storage environment that reduces corrosion (Corrostock).

• Minimally invasive anchoring system

  Mini-invasive anchoring, Suturing, Stapling, Electrical stimulation, Percutaneous implantation, Single incision laparoscopy, Soft tissue.

• Optical force transducer

  Medical device - Force Sensing - Force Feedback - Minimally invasive.

• Quasi-deterministic single photon source

  The quasi-deterministic heralded photon sources relies on an active frequency-multiplexing technique. Photons are generated independently in different frequency bins and many (100+) frequency bins are in principle available.

Environment & Energy

• Atmospheric plasma deposition of Crystalline inorganic coatings

  The invention of an induction heating system adapted to a reactor of the 'dielectricbarrier discharge' type known as DBD, opened up the field of crystalline deposits of inorganic material hitherto limited to deposition under vacuum or at very high temperature.

• Cellulose Derived Biopesticide Activating the Plant Immune System

  Phytopharmaceutical compositions based on cellobionic acid to trigger plant defense responses, thus enhancing plant resistance to pathogens.

• Environmentally-friendly process for recovering gold from Waste from Electrical and Electronic Equipment (WEEE or e-waste)

  A gold leaching solution using environmentally-friendly chemistry, easy to implement and allowing an easy recovery of dissolved gold downstream of the process.

Contact:

Arnaud Quintens 
IP management and transfer unit ULB-KTO
arnaud.quintens@ulb.be
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See the ULB-KTO team