Phylogénie moléculaire des organismes

Theoretical courses (9h)

• Main principles of the classification of living organisms
• History of molecular phylogeny and major molecular discoveries
• Choice of molecular markers
• Sequence alignments
• Phylogenetic inference methods
• Concrete examples & Solving the tree of life

Practical sessions (2 x 3h) (use of the student’s personal laptop is recommended)

• Use of sequence analysis and phylogenetic inference tools

The course aims at introducing students to the theoretical notions of phylogenetic inference so that they can understand the different methods discussed in scientific publications but also master some bioinformatics tools allowing them to infer phylogenetic trees and interpret them.

Required and Corequired knowledge and skills

Basic biochemistry and molecular biology; use of a personal computer and the Internet.

Conferences
Practical sessions in computer room (2x3h)

References, bibliography, and recommended reading

• Yang, Z., & Rannala, B. (2012). Molecular phylogenetics: principles and practice. Nature reviews genetics, 13(5), 303-314.
• Giribet, G., & Edgecombe, G. D. (2020). The invertebrate tree of life. Princeton University Press.
• Hall, B. G. (2004). Phylogenetic trees made easy. WH Freeman.
• Kumar, S., Nei, M., Dudley, J., & Tamura, K. (2008). MEGA: a biologist-centric software for evolutionary analysis of DNA and protein sequences. Briefings in bioinformatics, 9(4), 299-306.
• Tamura, K., Dudley, J., Nei, M., & Kumar, S. (2007). MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Molecular biology and evolution, 24(8), 1596-1599.

Course notes

• Université virtuelle

Additional information

Theoretical courses: UMONS, Campus de la plaine (co-modal teaching)
Practical sessions: UMONS, Campus de la plaine (presential teaching)

Course materials available on Moodle

Contacts

Igor Eeckhaut, Jérôme Delroisse

Campus

UMons

Method(s) of evaluation

• Oral examination

Oral examination

Oral examination
Oral presentation (“Phylogeny question”)

Mark calculation method (including weighting of intermediary marks)

Oral examination 50%
Oral presentation 50%

Language(s) of evaluation

• french
• (if applicable english )